ࡱ> 'RdO) APowerPoint Document(KSummaryInformation(DocumentSummaryInformation8D )( !"#$%&*+,-./0123453( b/ 0DTimesp0 8 8N`NN`DSymbolp0 8 8N`NN` ` .  @n?" dd@  @@`` x8  c $@euʚ;2Nʚ;g4xdxd `NtT ppp@ <4!d!d pg8<4dddd pg8 <4BdBd p8j___PPT9LD,h___PPT2001D<4X? %Pathogenomics in France Philippe GlaserAdministrative situation tCreation of the ANR (Agence National pour la Recherche) - National Research Agency Delay due to the need of a law Headed by Gilles Bloch Budget 350 M Infectious diseases is one of the priority Financial basis for future transnational program BUT the administrative person in charged of this topic is not nominated*SS*   #Research agenda-situation in France$$($ All major pathogenic species are studied in France, a weakness on streptococci (>80 teams) The different fields of the agenda from ecology and epidemiology to cell microbiology are covered Fundamental and applied research + development (innovation) Genomics platforms Sequencing facility (CNS, Institut Pasteur, Marseille) Transcriptome platforms (production and scanning) Proteome analysis Weakness: metabolome analysis Few screens of active molecules (inhibitors) T ZZ-ZZ .b&     @   7   Research teams in the filed of Pathogenomics belong to various administrative structures: INSERM INRA CNRS Institut Pasteur CEA Universities Hospitals Industries Need to improve networking and collaborations hZZHZ.ZZZH.F  >   ]  9Many French teams are involved in European collaborations::(: Bilateral collaboration Part of existing European networks (NoE, IP, STREP) Contribute to the submission of project which have not been retained*<  R Collaboration - Genomics >Analysis of the need of new genome sequences (environmental samples, hyper-virulent clones & ) Information exchange and common genomic databases (also before submission to public sequence databases) Cooperation in genome annotation and re-annotation (species-genome) The human metagenome       +Transcriptomics - proteomics - metabolomics,,(*    Exchange of sets of oligonucleotides for major microorganisms. Improvement of the quality (there is a need). Chips production and exchange Other technical development in the field of transcriptomics and proteomics Data exchange and databases (difficult issue) Strengthening metabolomics Access to platform for the screening of diverse chemical compounds collections Production and exchange of transgenic mice Stimulate the production and exchange of other tools and methodological improvementsZb    K     )Expectations from this transnational call**$* Improve the evaluation of the project Stimulatory effect on the quality of the projects Create opportunities for new collaborations Provide the opportunity to initiate new research projects Opportunities for junior groups to be involved in international collaborations How to define the link with genomics? Increase the financial investment of the French research agency in this field. How to synchronize with national calls? What should be the priority topics? Z   ` 33` Sf3f` 33g` f` www3PP` ZXdbmo` \ғq>9y`Ӣ` 3f3ff` 3f3FKf` hk]wwwfܹ` ff>>\`Y{ff` R>&- {p_/̴>?" dd@,|?" dd@   " @ ` n?" dd@   @@``PR    @ ` ` p>> rj(  08nD    6/ "P  PCliquez et modifiez le titre H  04 "  vCliquez pour modifier les styles du texte du masque Deuxime niveau Troisime niveau Quatrime niveau Cinquime niveau4 w  0- "``  P*   0P4 "`   R*   02 "`   R* H  0޽h ? 33 *Nouvelle prsentation 0(  l  C 0*p $ l  C Y8 `   $ H  0޽h ? 33  @ (   l  C 0P  $ l  C p, $ H  0޽h ? 33  P(  l  C @}  $ l  C } @ $ H  0޽h ? 33d   `,(  ,l , C }`@`  $ H , 0޽h ? 33  p(  n@ l  C 0T8P  $ l  C } $ H  0޽h ? 33  ( F l  C }P  $ l  C } $ H  0޽h ? 33  0$(  0r 0 S }P  $ r 0 S } $ H 0 0޽h ? 33   4(  4l 4 C *P  $ l 4 C 00x $ H 4 0޽h ? 33dxp^RЀ3ÿ lHbP  @AL G@;b `B&VI)T嗔)?4Jnd~?4TmAZ8~.7I:~m?4C>I)T嗔)?4Jnd~?4TmAZ8~.7I:~m?4C>I)T嗔)?4Jnd~?4TmNAs"M<\x9H}%%ix9,O۪S%isV&г"%iۚ%ǻAs"M<\x9H}%%ix9,O۪S%isV&г"%iۚ%ǻAs"M<\x9H}%%ix9,O۪S%isV&г"%iۚ%E$NEQ_({M+U_$4?Z`)+U;$+UZMո$NEQ_({M+U_$4?Z`)+U;$+UZMո$NEQ_({M+U_$4?Z`)+U;$+UZMNA{!KDPj:}{+Uj:$4?fG+U;{!+Uf}{̻A{!KDPj:}{+Uj:$4?fG+U;{!+Uf}{̻A{!KDPj:}{+Uj:$4?fG+U;{!+Uf}{ZBp':,(m!KYF;{/mܣ٠ J.}w/pѬ':/J.F;{Bp':,(m!KYF;{/mܣ٠ J.}w/pѬ':/J.F;{Bp':,(m!KYF;{/mܣ٠ J.}w/pѬ':/J.F;{ Ǻw Ǻw Ǻw zlzlzlȱȱȱ 5      %"  tation PowerPoint:Many French teams are involved in European collaborationsCollaboration - Genomics,Transcriptomics - proteomics - metabolomics*Expectations from this transnational call Polices utiliséesModèle de conceptionTitres des diapositives_Krothmrothm/ 0DTimesP0;;@N`NN`DSymbolP0;;@N`NN` ` .  @n?" dd@  @@`` x8  c $@euʚ;2Nʚ;g4xdxd`NtTppp@ <4!d!d  g@<4dddd  g@ <4BdBd  @j___PPT9LD,h___PPT2001D<4X@? %+Pathogenomics in France Philippe GlaserAdministrative situation  tCreation of the ANR (Agence National pour la Recherche) - National Research Agency Delay due to the need of a law Headed by Gilles Bloch Budget 350 M Infectious diseases is one of the priority Financial basis for future transnational program BUT the administrative person in charged of this topic is not nominated*SS&   #Research agenda-situation in France$$( $ All major pathogenic species are studied in France, a weakness on streptococci (>80 teams) The different fields of the agenda from ecology and epidemiology to cell microbiology are covered Fundamental and applied research + development (innovation) Genomics platforms Sequencing facility (CNS, Institut Pasteur, Marseille) Transcriptome platforms (production and scanning) Proteome analysis Weakness: metabolome analysis Few screens of active molecules (inhibitors) T ZZ-ZZ .Z&     @   7   Research teams in the filed of Pathogenomics belong to various administrative structures: INSERM INRA CNRS Institut Pasteur CEA Universities Hospitals Industries Need to improve networking and collaborations Interaction with SMEs and Pharma hZZHZOZZZHOh  >   m     9Many French teams are involved in European collaborations::( : Bilateral collaboration Part of existing European networks (NoE, IP, STREP) Contribute to the submission of project which have not been retained&<  R Collaboration - Genomics  >Analysis of the need of new genome sequences (environmental samples, hyper-virulent clones & ) Information exchange and common genomic databases (also before submission to public sequence databases) Cooperation in genome annotation and re-annotation (species-genome) The human metagenome       +Transcriptomics - proteomics - metabolomics,,((    Exchange of sets of oligonucleotides for major microorganisms. Improvement of the quality (there is a need). Chips production and exchange Other technical development in the field of transcriptomics and proteomics Data exchange and databases (difficult issue) Strengthening metabolomics Access to platform for the screening of diverse chemical compounds collections Production and exchange of transgenic mice Stimulate the production and exchange of other tools and methodological improvementsZZ    K    )Expectations from this transnational call**$ * Improve the evaluation of the project Stimulatory effect on the quality of the projects Create opportunities for new collaborations Provide the opportunity to initiate new research projects Opportunities for junior groups to be involved in international collaborations How to define the link with genomics? Increase the financial investment of the French research agency in this field. How to synchronize with national calls? What should be the priority topics? Z  d   P,(  ,l , C @}`@`   H , 0޽h ? 33r1 J1K