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Researchers Database

You have entered the IISP: Interactive Information System on Pathogenomics


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Here you will find information about Research groups in the PathoGenoMics fields from the ERA-NET partner countries (Austria, Finland, France, Hungary, Israel, Latvia, Portugal, Slovenia and Spain).
This information is supposed to support cooperation between researchers from different European countries
and thus enhance the development of a European Research Area for PathoGenoMics .


The following information is available and can be searched for:

  • researcher names
  • Institution of the respective researcher, city and country of his/her institution
  • Contact data of the researcher (address, phone, email)
  • Research topics and studied microorganisms of the researcher
  • Special techniques applied by the researcher
  • Potential cooperation topics suggested by the researcher

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Name: Dr. Trieu Cuot, Patrick
Address: 25 rue du Dr ROUX
Institution: Institut Pasteur
City: Paris Zip: 75724
Country: France Phone:


Research Topics:
Virulence of Staphylococcus aureus and Streptococcus agalactiae; Gene regulation, resistance to oxydative stress, cell surface components and bacterial-host interactions. Our research is centered on the modification of gene expression in response to environmental signals, particularly stress response and two-component signal transduction, and the role of these systems in the virulence of Staphylococcus aureus and Streptococcus agalactiae. Our goal is to decipher the regulatory networks involved in the production of virulence factors and survival of pathogens within the host. Major research topics are: in vitro and in vivo gene regulation, bacterial-host interactions (adhesion, invasion, colonization), and biofilm formation.


Organisms studied:
  • Staphylococcus
  • Streptococcus agalactiae


Special methods / technologies:
Our research unit is well-equipped for the proposed research. Excellent facilities for DNA and protein analyses, and molecular biological studies on class 2 bacterial pathogens are available. We routinely use cellular (epithelial and phagocytic cell lines) and animal models suitable for the study of the virulence of S. aureus (Caenorhabditis elegans and murine infection models) and S. agalactiae (mice and neonate rats). In addition, our research unit has access to a noninvasive bioluminescence imaging system that enables to follow the bacterial dissemination and multiplication in living mice.


Suggestions for potential research cooperations:
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