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Researchers Database

You have entered the IISP: Interactive Information System on Pathogenomics


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Here you will find information about Research groups in the PathoGenoMics fields from the ERA-NET partner countries (Austria, Finland, France, Hungary, Israel, Latvia, Portugal, Slovenia and Spain).
This information is supposed to support cooperation between researchers from different European countries
and thus enhance the development of a European Research Area for PathoGenoMics .


The following information is available and can be searched for:

  • researcher names
  • Institution of the respective researcher, city and country of his/her institution
  • Contact data of the researcher (address, phone, email)
  • Research topics and studied microorganisms of the researcher
  • Special techniques applied by the researcher
  • Potential cooperation topics suggested by the researcher

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Name: Dr. Hebraud, Michel
Address: INRA site de Theix 63122 Saint-Genès Champanelle
Institution: SRV-Microbiologie
Country: France Phone: 04 73 62 46 70


Research Topics:
The main research topics of our group concern studies on adhesion and growth in biofilm of L. monocytogenes on abiotic surfaces, the characterization of biodiversity to assess the risk linked to L. monocytogenes, the stress adaptation and survival. Our research works are focused on (i) the characterisation of genes/proteins involved in adhesion and biofilm formation, (ii) the characterisation of subproteomes (intracellular, surface and secreted proteins), (iii) the study of biodiversity and the comparison of clinical, asymptomatic carriage and food plants strains of L. monocytogenes strains, (iv) the adaptative response to environmental variations and technological stresses (temperature, salt, alkaline and biocide treatments) and (v) the effects of selected decontamination processes on surfaces of food plants. For the characterization of sessile mode of growth, different models have been developed to form biofilms either on stainless steel, PTFE or glass fibers. Different approaches are used for these studies: the characterisation of physico-chemical properties of bacterial surfaces; the observation by scanning electron microscopy or fluorescence microscopy of the biofilm formation; the assessment of (i) adhesion ability and biofilm formation and (ii) the efficiency of selected cleaning disinfection processes (with Biofilm Control Sas startup); the characterization of genes of interest; the proteome and traductome characterization and variations by 2-D SDS-PAGE, the image analysis of 2-D gels (ImageMaster 2-D Platinium, GE Healthcare) and the identification of proteins of interest by mass spectrometry (Maldi-Tof MS or ESI-Ion Trap MS, INRA Proteomic platform, responsible : M. Hébraud).


Organisms studied:
  • Listeria monocytogenes


Special methods / technologies:
Genetic, proteomic, mass spectrometry, microscopy


Suggestions for potential research cooperations:
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